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Med Minute: Amoxicillin

Med Minute: Amoxicillin
A doctor examining a boy's throat and the title: Med Minute: Amoxicillin

In this Med Minute guide, we’re covering amoxicillin, a commonly prescribed antibiotic used to treat and prevent various bacterial infections. It works by stopping bacteria from growing and replicating, often requiring a 7 to 10-day course for full effectiveness. Keep reading for quick facts on uses, dosing, side effects, and tips for giving it to your child!

What's it commonly used for?

  • Treating bacterial infections: ear infections, pneumonia, skin infections, urinary tract infections, strep throat, sinus infections, Lyme disease 
  • Preventing bacterial infections (prophylaxis): dental procedures, urinary tract infections, sickle cell disease 

How does it work? 

  • It kills bacteria by preventing bacteria from building cell walls and preventing bacterial cells from replicating. 
  • Amoxicillin is a “time-dependent killer” that stops bacterial infections slowly, so therapy is often long, around 7-10 days. 

What's the dose? 

  • Varies depending on weight and what you are treating
  • Typical doses are around 45 mg/kg/day (standard) or 90 mg/kg/day (high) up to standard adult doses of 500-1000 mg per dose
  • High dose regimen is most commonly used for ear infections or pneumonia 
  • Usually given every 8 or 12 hours

What are the most common side effects? 

  • Diarrhea, nausea, vomiting
  • Headache
  • Rash (mild to severe) 
  • Tooth discoloration

How should my child take it? 

  • Take with or without food, taking with meals may reduce stomach upset 
  • Shake the suspension well and use the measuring device provided
  • Store suspension in the refrigerator 
  • You can mix it with formula, juice, water, or milk, but make sure your child drinks the whole thing
Andrea Morrissey, PharmD

This article has been reviewed by Andrea Morrissey, PharmD, Board Certified Pediatric Pharmacy Specialist, and Chief Content Officer of Kids Med Guide. The content is for educational and entertainment purposes only and does not replace professional medical advice. Always consult your healthcare provider for medical guidance, and call 911 in an emergency.

Kids Med Guide is not liable for your interpretation or reliance on this material. You assume full responsibility for its use and any resulting decisions.

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